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Lorraine Leon

Lorraine Leon

Assistant Professor

Phone: 407-823-5378
Office: ENG I, Room 210
Website: Biomolecular Engineering Lab


  • Ph.D. in Chemical Engineering, City University of New York, 2011
  • B.S. in Chemical Engineering, University of Florida, 2004


  • Molecular engineering  and self assembly
  • Biomaterials
  • Polyelectrolyte complexation
  • Soft materials characterization
  • Nanomedicine


  • A.B. Marciel, E.J. Chung, B.K. Brettmann, L. Leon, “Bulk and Nanoscale Polypeptide-Based Polyelectrolyte Complexes” Advances in Colloid and Interface Science 2016 DOI:10.1016/j.cis.2016.06.012
  • Priftis, L. Leon, Z. Song, S.L. Perry, K.O. Margossian, A. Tropnikova, J.J. Cheng, M. Tirrell, “Self-Assembly of α-Helical Polypeptides Driven by Complex Coacervation” Angewandte Chemie 2015, 127, 11280-11284 DOI:10.1002/anie.201504861
  • S.L. Perry*, L. Leon*, K. Hoffmann, M.J. Kade, D. Priftis, D. Wong, K. Black, C. Pierce, K. Margossian, J. Whitmer, J. Qin, J. de Pablo, M.V. Tirrell, “Chirality Selected Phase Transitions in Ionic Polypeptide Complexes” Nature Communications 2015, 6, 6052 DOI: 10.1038/ncomms7052
  • C-H Kuo*, L. Leon*; E.J. Chung, T.J. Sontag, C.A. Reardon, G.S. Getz, M.V Tirrell, Y. Fang, “Inhibition of Atherosclerosis-Promoting microRNAs via targeted polyelectrolyte complex micelles” Journal of Materials Chemistry B 2014, 2, 8142-8153 DOI: 10.1039/C4TB00977K
  • Leon, W. Su, H. Matsui, R.S. Tu, “Interfacial Templating of Inorganic Nanostructures Using a Growth Directing and Reducing Peptide” Soft Matter 2011, 7, 10285-10290 DOI: 10.1039/C1SM05906H
  • Leon, P. Logrippo, R.S. Tu, “Self-Assembly of Rationally Designed β-Sheets Under 2-D Confinement” Biophysical Journal 2010, 99, 2888-2896 DOI: 10.1016/j.bpj.2010.08.061


  • American Institute of Chemical Engineers
  • American Chemical Society
  • Materials Research Society